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epidermal melanocytes hema cell line  (Cell Applications Inc)


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    Cell Applications Inc epidermal melanocytes hema cell line
    Epidermal Melanocytes Hema Cell Line, supplied by Cell Applications Inc, used in various techniques. Bioz Stars score: 94/100, based on 29 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/epidermal melanocytes hema cell line/product/Cell Applications Inc
    Average 94 stars, based on 29 article reviews
    epidermal melanocytes hema cell line - by Bioz Stars, 2026-02
    94/100 stars

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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the NHEM cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.

    Journal: Molecular medicine reports

    Article Title: Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.

    doi: 10.3892/mmr.2019.10798

    Figure Lengend Snippet: Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the NHEM cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.

    Article Snippet: The normal human epidermal melanocyte (nHeM) cell line was provided by cell applications inc. and cultured in M2 medium.

    Techniques: Expressing, Software, Control, Standard Deviation